laboratory of Medical Engineering SCHOOL OF MEDICINE
Aplicaciones anidadas
Aplicaciones anidadas
Lab_Cita
The laboratory of Medical Engineering arises from a vital need: to achieve the perfect tandem between doctors and engineers.
Lab_Texto_Principal
SINCE 2015
The School of Medicine of the University of Navarra has a pioneering laboratory of Medical Engineering. Created in 2015, its goal is to provide engineering solutions to the healthcare environment through the close partnership that exists between the different Departments of the School, services of the Clínica Universidad de Navarra, the laboratories of the research center Applied Medicine (CIMA) and the School of Engineering (Tecnun).
Aplicaciones anidadas
Lab_Texto_Lineas_Trabajo
LINES OF WORK
Lab_Texto_Lineas_Trabajo1
Simulation
Lab_Texto_Lineas_Trabajo2
Quantification of physiological
physiological variables
8 Clinical cases 6 Support in management 51 design and manufacturing
Lab_Titulo_Ejemplos
WORK SUCCESS STORIES FROM THE LABORATORY
Aplicaciones anidadas
Lab_Ejemplos_Texto1
Characterization of adipose tissue
This project arose as a result of a research need of the Clínica Universidad de Navarra. Members of laboratory carried out a research and elaborated a doctoral thesis to answer the problem. From there, several articles were written, including one published in the scientific journal certificate Biomaterialia.
Lab_Ejemplos_Imagen1
Lab_Ejemplos_Texto2
Laparoscopy simulator
This project arises from the need of the Simulation Center and is being employee also in the Clínica Universidad de Navarra and in activities of the conference Surgery for Students (JOICE). Students from different Degrees performed an interdisciplinary work of design, fabrication and validation as part of their Final Projects Degree.
Lab_Ejemplos_Imagen2
Lab_Ejemplos_Texto3
Surgical planning
This project arises from a surgical need of a patient from the Clínica Universidad de Navarra. Professionals from the Clinic and the laboratory worked together to develop a specific 3D model for a patient with craniosynostosis. From this work emerged a article that is collected in the book Neurosurgery published in 2017.
Lab_Ejemplos_Imagen3
Aplicaciones anidadas
Aplicaciones anidadas
Lab_Texto_Estrategia2025
STRATEGY 2025
The laboratory of Medical Engineering financial aid with its work to pursue the objectives of the Strategy 2025 proposed by the University. This Strategy proposes to contribute to the resolution of the challenges posed by society through its work researcher , professor and assistance, and in partnership with other people and institutions. The laboratory is aligned with the three lines of action:
Aplicaciones anidadas
Lab_Estrategia_Titulo1
EDUCATION TRANSFORMER
Lab_Estrategia_Texto1
TFG and internships in which the student is the owner of its project making decisions.
Aplicaciones anidadas
Lab_Estrategia_Titulo2
RESEARCH IMPACT AND FOCUS
Lab_Estrategia_Texto2
Projects with a clear practical purpose seeking the implementation and solution of real problems.
Aplicaciones anidadas
Lab_Estrategia_Titulo3
INTERDISCIPLINARY UNIVERSITY
Lab_Estrategia_Texto3
Courses and TFGs together with several Degrees (Final Projects Degree joint between Biomedical Engineering, design industrial and Medicine).
- Llorente-Ortega M, Polo R, Chiva S, et al. The development and validation of a new simulator for endourology. conference proceedings Urológicas Españolas (English Ed. January 2023. doi:10.1016/j.acuroe.2023.01.004
- Llorente-Ortega M, Podhorski A, Fernandez S. Introducing a New Dosimeter for the Assessment and Monitoring of board member Risk Situations and Voice Disorders. J Voice. October 2022. doi:10.1016/j.jvoice.2022.08.007.
- Martín-Calvo N, Gómez B, Díez N, et al. Development and validation of a low-cost laparoscopic simulation box. Cirugía Española (English Ed. August 2022. doi:10.1016/j.cireng.2022.07.033
- Morer-Camo P, Paredes-Puente J, Llorente-Ortega M, Unamuno-Iñurritegui X. Design of a Neurosurgery Training Simulator with Additive Manufacturing to Practice the Suture of the Dura Mater. In: ; 2022:182-190. doi:10.1007/978-3-030-92426-3_22.
- Unamuno X, Gómez-Ambrosi J, Becerril S, et al. Changes in mechanical properties of adipose tissue after bariatric surgery driven by extracellular matrix remodelling and neovascularization are associated with metabolic improvements. certificate Biomater. 2022;141:264-279. doi:10.1016/j.actbio.2022.01.007
- Catalán V, Rodríguez A, Becerril S, et al. The 'new normality' in research? What message are we conveying our medical students? Eur J Clin Invest. 2021;51(9). doi:10.1111/eci.13586
- Díez N, Pacheco S, Llorente M, Fernández S. Validation of a Sensor-Fitted Simulator for Upper Airway Examination. Otolaryngol Neck Surg. 2021;164(2):339-345. doi:10.1177/0194599820941017.
- Frühbeck G, Mentxaka A, Ahechu P, et al. The Differential Expression of the Inflammasomes in Adipose Tissue and Colon Influences the Development of Colon Cancer in a Context of Obesity by Regulating Intestinal Inflammation. J Inflamm Res. 2021;Volume 14:6431-6446. doi:10.2147/JIR.S335882
- Llorente M, Fernández S. Design and Development of an Automated Feedback and Scoring System for Self-directed Learning of Flexible Nasal Endoscopy With an Airway Simulator. Simul Healthc J Soc Simul Healthc. 2021;16(5):367-371. doi:10.1097/SIH.0000000000000522.
• Besné GM, Alegre M, Podhorski A, Díez N. Validity evidence of <scp>SIMUL</scp> ‐Eye: eye movement and pupillary reflex simulator. Acta Ophthalmol. 2020;98(3). doi:10.1111/aos.14209
- Guarnieri A, Carnero E, Bleau A-M, López de Aguileta Castaño N, Llorente Ortega M, Moreno-Montañés J. Ocular surface analysis and automatic non-invasive assessment of tear film breakup location, extension and progression in patients with glaucoma. BMC Ophthalmol. 2020;20(1):12. doi:10.1186/s12886-019-1279-7
- Rodríguez A, Catalán V, Ramírez B, et al. Impact of adipokines and myokines on fat browning. J Physiol Biochem. 2020;76(2):227-240. doi:10.1007/s13105-020-00736-2
- Becerril S, Rodríguez A, Catalán V, et al. iNOS Gene Ablation Prevents Liver Fibrosis in Leptin-Deficient ob/ob Mice. Genes (Basel). 2019;10(3):184. doi:10.3390/genes10030184
- Becerril S, Rodríguez A, Catalán V, et al. Functional Relationship between Leptin and Nitric Oxide in Metabolism. Nutrients. 2019;11(9):2129. doi:10.3390/nu11092129.
- Becerril S, Rodríguez A, Catalán V, et al. Targeted disruption of the iNOS gene improves adipose tissue inflammation and fibrosis in leptin-deficient ob/ob mice: role of tenascin C. Int J Obes. 2018;42(8):1458-1470. doi:10.1038/s41366-018-0005-5
- Jiménez Ormabera B, Díez Valle R, Zaratiegui Fernández J, Llorente Ortega M, Unamuno Iñurritegui X, Tejada Solís S. 3-D printing in neurosurgery: model specific for patients with craniosynostosis. Neurocirugia. 2017;28(6):260-265. doi:10.1016/j.neucir.2017.05.001
- "Simulators and self-directed learning for residents: ultrasound-guided interventional procedures" FJ. Mendaoza, M. Sáinz, JR Isasi, M. Domeño, P Alzuguren, M. Llorente, S. Fernández, FJ. Pueyo, J. Ciro. SERAM. Málaga, 2022.
- "development and validation of a laparoscopic simulation box" N. Martín-Calvo, B. Gómez, N. Díez, M. Llorente, S. Fernández, FJ. Pueyo. SESSEP. Granada, 2021.
- "Simulation in neurosurgery: creation of a pterional approach cranial model using segmentation software and 3D printing" OM. Parras, A. Arcadi, M. Macias, VR. Paradells, S. Fenández, X. Unamuno, M. Llorente. SENEC. Madrid, 2021.
- "Obesity triggers NLRP3-dependent adipose tissue low-grade inflammation and extracellular matrix remodelling" X. Unamuno, J. Gómez-Ambrosi, B. Ramírez, A. Rodríguez, S. Becerril, V. Valent, R. Moncada, C. Silva, J. Salvador, G. Frühbeck, V. Catalán. ECOICO. Dublin, 2020.
- "Validation of two new simulators of neuraxial anesthesia: students vs anaesthetists" S. Rubio, J. Pueyo, X. Unamuno, M. Llorente, S. Fernandez, C. Honorato. SESAM. Bilbao, 2018.
- "Design of a wearable device for voice monitoring" M. Llorente, A. Podhorski, S. Fernández. ELSOC. London, 2018.
- "SIMUL-Eye: simulator of normal and pathological eye movements and pupillary reflexes" G. Besné, N. Díez, M. Alegre. SESSEP. Murcia, 2017.
- "The matricellular adipokine dermatopontin regulates adipose tissue extracellular matrix remodelling and inflammation in obesity" X. Unamuno, J. Gómez-Ambrosi, B. Ramírez, A. Rodríguez, S. Becerril, V. Valentí, R. Moncada, C. Silva, J. Salvador, G. Frühbeck, V. Catalán. EASO. Malaga 2021.
- "The role of simulation in endourology training: development and validation of a 3D-printed model" S. Chiva, R. Polo, C. Muñoz, J. Colombas, C. Gutierrez, P. Domenech, F.J. Diez-Caballero, M. Llorente, F.J. Ancizu, M. Torres, L. Labairu, D. Rosell, J. Robles, F. Ramón de Fata, F. Villacampa, G. Barbas, G. Andrés, B. Miñana, J. Pascual. EAU. Madrid, 2021.
- "NLRP3 as an adipose tissue low-grade inflammation and extracellular matrix remodeling activator in obese subjects" X. Unamuno, J. Gómez-Ambrosi, B. Ramírez, A. Rodríguez, S. Becerril, V. Valentí, R. Moncada, C. Silva, J. Salvador, G. Frühbeck, V. Catalán. CIBEROBN Annual Symposium. Madrid, 2020.
- "NLRP3 inflammasome as a mediator of inflammation and extracellular matrix remodeling in obesity-associated non-alcoholic fatty liver disease" X. Unamuno, J. Gómez-Ambrosi, B. Ramírez, A. Rodríguez, S. Becerril, V. Valentí, R. Moncada, C. Silva, G. Frühbeck, V. Catalán. ESCI. Bari, 2020.
- "Increased adiponectin/leptin ratio in patients with obesity and type 2 diabetes after Roux-en-Y gastric bypass" X. Unamuno, M. Izaguirre, J. Gómez-Ambrosi, A. Rodríguez, B. Ramírez, S. Becerril, V. Valentí, R. Moncada, C. Silva, J. Salvador, P. Portincasa, G. Frühbeck, V. Catalán. XIII workshop of research in experimental and health sciences. Pamplona, 2020.
- "Roux-en-Y Gastric Bypass Increases the Adiponectin/Leptin Ratio in Patients with Obesity and Type 2 Diabetes" X. Unamuno, M. Izaguirre, J. Gómez-Ambrosi, A. Rodríguez, B. Ramírez, S. Becerril, V. Valentí, R. Moncada, C. Silva, J. Salvador, P. Portincasa, V. Catalán, G. Frühbeck. CIBEROBN Annual Symposium . Madrid, 2019.
- "Impact of mini-gastric bypass and sleeve gastrectomy on adiposity and blood pressure in diet-induced obese rats" X. Unamuno, S. Becerril, A. Rodríguez, JA. Cienfuegos, V. Valentí, J. Gómez-Ambrosi, B. Ramírez, S. Ezquerro, L. Méndez-Gimenez, M. Martín, MA. Burrell, V. Catalán, MR. Elizalde, G. Frühbeck. ECO. Glasgow, 2019.
- "design of a wearable device for voice monitoring" M. Llorente, A. Podhorski, S. Fernández. XII workshop of research in Experimental and Health Sciences. Pamplona, 2019.
- "Impact of mini-gastric bypass on adiposity and blood pressure in diet-induced obese rats" X. Unamuno, S. Becerril, A. Rodríguez, JA .Cienfuegos, V. Valentí, J. Gómez-Ambrosi, B. Ramírez, S. Ezquerro, L. Méndez-Gimenez, M. Martín, MA. Burrell, V. Catalán, M. Reyes Elizalde, G. Frühbeck. CIBEROBN Annual Symposium. Madrid, 2018.
- "Effects of Roux-en-Y gastric bypass on adiposity and blood pressure in diet-induced obese rats" X. Unamuno, S. Becerril, A. Rodríguez, JA. Cienfuegos, V. Valentí, J. Gómez-Ambrosi, B. Ramírez, S. Ezquerro, L. Méndez-Gimenez, M. Martín, MA. Burrell, V. Catalán, MR. Elizalde, G. Frühbeck. ESCI. Barcelona, 2018.
-award UCAM - SEORLCCC for the Best work in Voice Pathology" S. Fernández, M. Llorente-Ortega, N. López-de-Aguileta, S. Ferrán, D. Terrasa. SEORL. Las Palmas, 2022.
- 3rd prize Bio Art Award" X. Unamuno. ESCI. 2020.
- "1st award Action of training, transformation, information or health awareness" laboratory of Medical Engineering. 2018.
- "2nd award BINVA" M. Llorente, X. Unamuno, E. Cristóbal. 2017.
